Efficacy of wound cleanser 25% based on Indonesian medicine plants on chronic wound healing

Julianto, Eko and Julianus, Julianus and Suandika, Made and Agustin, Ayu Tri and Julianus, Julianus and Riranto, Jepri (2023) Efficacy of wound cleanser 25% based on Indonesian medicine plants on chronic wound healing. Riset Informasi Kesehatan, 12 (1): 1. pp. 1-7. ISSN 2548-6462

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Abstract

Background: Chronic wounds are a challenge for wound care professionals and a global
economic burden that has increased morbidity and mortality in patients worldwide.
Purpose: This study aims to determine the efficacy of wound cleanser with guava leaf extract
(Psidium guajava Linn) and betel leaf extract (Piper betle L) 25% on the inhibition of bacterial
growth in chronic wounds.
Methods: The research conducted was laboratory experimental in nature. Guava leaf extract
(Psidium guajava Linn) and betel leaf extract (Piper betle L) were formulated in the form of liquid
soap with a concentration of 25% then evaluation of the physical preparations, allergy tests and
bacterial tests were carried out in the form of the inhibition of liquid soap against Pseudomonas
aeruginosa bacteria, Staphylococcus aureus, Escherichia coli in chronic wounds, Bacillus subtilis,
Bacillus cereus, Staphylococcus epidermidis and Yeast Candida Albicans. Data collection is
carried out after passing the ethical test.
Results: This proves that liquid soap preparations of ethanol extract of guava leaves (Psidium
guajava Linn) and betel leaf extract (Piper betle L) have medium, strong and very strong inhibition
against Pseudomonas aeruginosa (12.28 mm), Staphylococcus aureus (19.48 mm), Escherichia
coli (13.94 mm), Bacillus subtilis (27.58 mm), Bacillus cereus (11.11 mm), Staphylococcus
epidermidis (14.44 mm) and category of respond medium inhibition on Yeast Candida Albicans
(8.13 mm).
Conclusion: Based on the results of the study, it can be concluded that the formulation of liquid
soap preparations of ethanol extract of guava leaves (Psidium guajava Linn) and betel leaf extract
(Piper betle L) with a concentration of 25% fulfills the quality requirements for liquid soap
preparations. The results of this liquid soap antibacterial test had a strong response in inhibiting
the growth of the bacteria Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli,
Bacillus cereus, Staphylococcus epidermidis.

Item Type:	Article
Subjects:	R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica R Medicine > RT Nursing
Divisions:	Program Studi > D3 Keperawatan
Depositing User:	Eko Julianto
Date Deposited:	28 Aug 2023 09:17
Last Modified:	28 Aug 2023 09:17
URI:	http://repository.politeknikyakpermas.ac.id/id/eprint/930

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