UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN MIMBA, SAMBANG DARAH DAN NILAM TERHADAP MYCOBACTERIUM TUBERCULOSIS

Julianto, Eko (2019) UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN MIMBA, SAMBANG DARAH DAN NILAM TERHADAP MYCOBACTERIUM TUBERCULOSIS. Mahakam Nursing Journal, 2 (6). pp. 1-6. ISSN 2548-6292

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Abstract

Tuberculosis (TB) is a disease main cause of death in the world. According to WHO in 2013, there were 8.6 million TB cases.. TB is a disease caused by a complex Mycobacterium tuberculosis infection. In general, TB disease is treated using Anti Tuberculosis (OAT) drugs such as Rifampicin and has not beenfound with many medicinal plants or herbs. From medicinal plants or herbs, there are activities which inhibit Mycobacterium tuberculosis. This study used laboratory experimental methods including maceration of mimba's leaf, nilam's leaf and sambang darah's leaf in 70% ethanol. Then the antibacterial activity was tested with a negative control comparison standard. The independent variables, namely the concentration of extract mimba's leaf, nilam's leaf sambang darah's leaf, and the dependent variable,namely the growth of colonies from Mycobacterium tuberculosis. Based on data analysis, 3 extracts are statistically significant differences. Third-week monitoring (3) showed that the results of data were normally distributed and the significant value in the ANOVA test was 0.001 <0.05, so it could be concluded that there was a significant difference in the average percentage of colony inhibition in each treatment group. In the LSD test, it was known that the combination of extract nilam's leaf and extract sambang darah's leaf (group F) 125μg / ml had the largest average value of inhibition of colony inhibition with 71.4% of colony inhibition percentage.

Keywords: extract mimba's leaf, extract nilam's leaf, extract sambang darah's leaf, mycobacterium tuberculosis

Item Type:	Article
Subjects:	R Medicine > RT Nursing
Divisions:	Institusi > Jurnal
Depositing User:	Eko Julianto
Date Deposited:	01 Sep 2021 01:42
Last Modified:	01 Sep 2021 01:42
URI:	http://repository.politeknikyakpermas.ac.id/id/eprint/249

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